Searchable abstracts of presentations at key conferences in endocrinology

ea0016p307 | Endocrine tumours | ECE2008

VDR gene polymorphisms in patients with differentiated thyroid cancer

Penna-Martinez Marissa , Stern Julienne , Kahles Heinrich , Reusch Jurgen , Hinsch Nora , Hansmann Martin-Leo , Selkinski Ivan , Grunwald Frank , Wahl Robert , Holzer Katharina , Ramos-Lopez Elizabeth , Badenhoop Klaus

Background/aim: Vitamin D receptor (VDR) expression has been shown to be upregulated in several tumors and is thought to represent an important endogenous response to tumor progression. Therefore, in order to evaluate the role of VDR-gene and of the 25(OH)-Vitamin D3 in thyroid cancer we analysed four polymorphisms in patients with thyroid cancer and healthy controls.Patients and methods: Patients (n=136; 84 females and 52 males) with d...